Document Detail


Dynamics of macaque MT cell responses to grating triplets.
MedLine Citation:
PMID:  22699905     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Neurons in area MT are sensitive to the direction of motion of gratings and of plaids made by summing 2 gratings moving in different directions. MT component direction-selective (CDS) neurons respond to the individual gratings of a plaid. Pattern direction-selective (PDS) neurons on the other hand, combine component information and respond selectively to the resulting pattern motion. Adding a third grating creates a "triplaid," which contains 3 grating and 3 plaid motions and is perceptually multistable. To examine how direction-selective mechanisms parse the motion signals in triplaids, we recorded MT responses of anesthetized and awake macaques to stimuli in which 3 identical moving gratings whose directions were separated by 120° were introduced in 3 successive epochs, going from grating to plaid to triplaid. CDS and PDS neurons-selected based on their responses to gratings and plaids-had strikingly different tuning properties in the triplaid epoch. CDS neurons were strongly tuned for the direction of motion of individual gratings, but PDS neurons nearly lost their selectivity for either the gratings or the plaids in the stimulus. We explain this reduced motion selectivity with a model that relates pattern selectivity of PDS neurons to a broad pooling of V1 afferents with a near-cosine weighting profile. Because PDS neurons signal both component and pattern motion in gratings and plaids, their reduced selectivity for motion in triplaids may be what makes these stimuli perceptually multistable.
Authors:
Mehrdad Jazayeri; Pascal Wallisch; J Anthony Movshon
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  32     ISSN:  1529-2401     ISO Abbreviation:  J. Neurosci.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-15     Completed Date:  2012-09-24     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  8242-53     Citation Subset:  IM    
Affiliation:
Center for Neural Science, New York University, New York, New York 10003, USA. mjaz@u.washington.edu
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MeSH Terms
Descriptor/Qualifier:
Action Potentials / physiology
Animals
Female
Fixation, Ocular / physiology
Macaca
Male
Motion Perception / physiology*
Neurons / physiology
Photic Stimulation / methods
Visual Cortex / physiology
Visual Pathways / physiology*
Wakefulness / physiology
Grant Support
ID/Acronym/Agency:
EY02017/EY/NEI NIH HHS; EY04440/EY/NEI NIH HHS; F32-EY019833/EY/NEI NIH HHS; P30 EY013079/EY/NEI NIH HHS; R01 EY002017/EY/NEI NIH HHS; R01 EY004440/EY/NEI NIH HHS
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