| Dynamic vs. fixed bag filling: impact on cardiac output rebreathing protocol. | |
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MedLine Citation:
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PMID: 20085827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to compare the repeatability (2.77 multiplied by the within-subject SD)between two different rebreathing protocols on cardiac output ( ˙Q ), pulmonary diffusing capacity for carbon monoxide (DLCO) and nitric oxide (DLNO), and pulmonary capillary blood volume (Vc). This study compared two bag volume protocols [Fixed Bag Volume (FBV) = bag volume fixed at 60% of forced vital capacity; Dynamic Bag Volume (DBV) = bag volume matched to tidal volume at each stage of exercise].Ten females (age = 27±8 yrs; ˙VO2, (peak)=2.5±0.6 L/min had measurements at rest (12%), 52%, 88%, and 100% of ˙VO2, (peak) on two study days. Neither the slope nor intercept of ˙Q vs. ˙VO2 were different between either bag volume protocols. The slope of DLCO vs. ˙Q was the same but the intercept was higher for the FBV protocol. The bag volume affected the slope and the intercept between DLNO vs. ˙Q (p < 0.05).The mean repeatability was similar between both protocols for ˙Q (2.0 vs. 2.3 L/min) and DLCO (3.8 vs.5.9 mL/min/mmHg), regardless of exercise intensity. Increasing exercise intensity made the measurement error worse for Vc and DLNO (p ≤ 0.06). Measurement error was lower for Vc when using the FBV protocol (p = 0.02). Also, the pattern of bag volume used during rebreathing maneuvers affected the relation between DLNO vs. ˙Q more than it affected DLCO vs. ˙Q , or Vc vs. ˙Q. Additionally, the FBV protocol provided less measurement error for Vc compared to the DBV protocol [corrected]. |
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Authors:
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Gerald S Zavorsky; Kenneth C Beck; Lauren M Cass; Raul Artal; Peter D Wagner |
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Publication Detail:
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Type: Journal Article Date: 2010-01-18 |
Journal Detail:
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Title: Respiratory physiology & neurobiology Volume: 171 ISSN: 1878-1519 ISO Abbreviation: Respir Physiol Neurobiol Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-29 Completed Date: 2010-06-23 Revised Date: 2012-03-14 |
Medline Journal Info:
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Nlm Unique ID: 101140022 Medline TA: Respir Physiol Neurobiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 22-30 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Obstetrics, Gynecology and Women's Health, School of Medicine, Saint Louis University, Saint Mary's Health Center, Saint Louis MO 63117, USA. zavorsky@slu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carbon Monoxide / blood Cardiac Output / physiology* Exercise Exercise Test / methods Female Humans Middle Aged Nitric Oxide / blood Oxygen / blood Oxygen Consumption Pulmonary Diffusing Capacity* Regression Analysis Respiratory Function Tests / methods Respiratory Mechanics / physiology* Rest Young Adult |
| Chemical | |
Reg. No./Substance:
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10102-43-9/Nitric Oxide; 630-08-0/Carbon Monoxide; 7782-44-7/Oxygen |
| Comments/Corrections | |
Erratum In:
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Respir Physiol Neurobiol. 2012 Mar 15;180(2-3):353-4 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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