| Dynamic regulation of mitochondrial function in preimplantation embryos and embryonic stem cells. | |
| | |
MedLine Citation:
|
PMID: 21168533 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Mitochondrial function is dependent upon regulation of biogenesis and dynamics. A number of studies have documented the importance of these organelles in both preimplantation embryos and embryonic stem cells (ESCs), however it remains unclear how mitochondria respond to their immediate microenvironment through modulation of morphology and movement, or whether perturbations in these processes will have a significant impact following differentiation/implantation. Here we review existing literature on two key aspects of nuclear-mitochondrial cross-talk and the dynamic processes involved in mediating mitochondrial function through regulation of mitochondrial biogenesis, morphology and movement, with particular emphasis on embryos and ESCs. |
| | |
Authors:
|
Alexandra Harvey; Tiffini Gibson; Thomas Lonergan; Carol Brenner |
Related Documents
:
|
22687253 - Anti-tumor and pro-apoptotic activity of ethanolic extract and its various fractions fr... 21075313 - Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversi... 19134553 - Overexpression of gadd34 enhances production of recombinant human antithrombin iii in c... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2010-12-17 |
Journal Detail:
|
Title: Mitochondrion Volume: - ISSN: 1872-8278 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2011-1-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100968751 Medline TA: Mitochondrion Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2010 Elsevier B.V. and Mitochondria Research Society. All rights reserved. |
Affiliation:
|
Department of Physiology, Wayne State University School of Medicine, Detroit, MI, 48201, United States. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Drosophila delta-1-pyrroline-5-carboxylate dehydrogenase (P5CDh) is required for proline breakdown a...
Next Document: Hesperetin protects testicular toxicity of doxorubicin in rat: Role of NF?B, p38 and caspase-3.