Document Detail

Dynamic outflow tract obstruction in congenitally corrected transposition of the great arteries.
MedLine Citation:
PMID:  20191324     Owner:  NLM     Status:  MEDLINE    
Congenitally corrected transposition of the great arteries (CCTGA) is a rare form of congenital heart disease, constituting 0.5% of all congenital heart defects. The incidence of left ventricle (non-systemic ventricle) outflow tract obstruction ranges between 44 and 57%. Herein, we present the case of a 45 year old woman with CCTGA with progressively worsening dyspnea who had been referred for surgical correction of severe systemic ventricle (morphologic right ventricle) atrio-ventricular valve (tricuspid valve) regurgitation. Cardiac magnetic resonance imaging (CMR) and transesophageal imaging (TEE) demonstrated severe systemic ventricle (morphologic right ventricle) contractile dysfunction, as well as dynamic non-systemic ventricle (morphologic left ventricle) outflow tract obstruction due to systolic anterior motion (SAM) of the non-systemic ventricle (morphologic left ventricle) atrio-ventricular valve (mitral valve) with a large membranous ventricular septal aneurysm that protrudes into the outflow tract of the non-systemic ventricle (morphologic left ventricle). Ultimately, our patient was felt to be too high-risk for surgical correction and a course of medical therapy has been pursued.
Andrew O Zurick; Venu Menon
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-02-27
Journal Detail:
Title:  The international journal of cardiovascular imaging     Volume:  26     ISSN:  1875-8312     ISO Abbreviation:  Int J Cardiovasc Imaging     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-07     Completed Date:  2010-10-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100969716     Medline TA:  Int J Cardiovasc Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  617-9     Citation Subset:  IM    
Heart & Vascular Institute, Department of Cardiovascular Medicine, Cleveland Clinic, Desk J1-5, Cleveland, OH 44195, USA.
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MeSH Terms
Dyspnea / etiology
Echocardiography, Doppler
Echocardiography, Transesophageal
Heart Aneurysm / etiology
Heart Valve Diseases / etiology
Magnetic Resonance Imaging
Middle Aged
Transposition of Great Vessels / complications*
Ventricular Outflow Obstruction / diagnosis,  etiology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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