| Dynamic observation of pulmonary perfusion using continuous arterial spin-labeling in a pig model. | |
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MedLine Citation:
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PMID: 11477677 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The continuous arterial spin-labeling (CASL) method of perfusion MRI is used to observe pulmonary perfusion dynamically in an animal model. Specifically, a respiratory-triggered implementation of the CASL method is used with approximate spatial resolution of 0.9 x 1.8 x 5.0 mm (0.008 cc) and 2-minute temporal resolution. Perfusion MRI is performed dynamically during repeated balloon occlusion of a segmental pulmonary artery, as well as during pharmacological stimulation. A total of three Yorkshire pigs were studied. The results demonstrate the ability of the endogenous spin-labeling method to characterize the dynamic changes in pulmonary perfusion that occur during important physiological alterations. |
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Authors:
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D A Roberts; R R Rizi; D A Lipson; M A Ferrante; L Bearn; L Rolf; J Baumgardner; A Yamomoto; H Hatabu; J Hansen-Flaschen; W B Gefter; M D Schnall |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 14 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-07-30 Completed Date: 2001-09-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 175-80 Citation Subset: IM |
Copyright Information:
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Copyright 2001 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104-4283, USA. roberts@oasis.rad.upenn.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Balloon Occlusion Lung / anatomy & histology* Magnetic Resonance Imaging / methods* Perfusion Pulmonary Artery Pulmonary Circulation Spin Labels Swine |
| Grant Support | |
ID/Acronym/Agency:
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RR02305/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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