Document Detail


Dynamic evaluation of prognosis from time-dependent variables in acute myocardial infarction.
MedLine Citation:
PMID:  6858861     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For predicting the 3 endpoints death, cardiac arrest, and cardiogenic shock within 44 days after admission for acute myocardial infarction (MI), a competing risk variant of the Cox multivariate model was developed. The population consisted of 1,140 patients with definite MI admitted within 24 hours of onset of symptoms. Prognostic variables from the entire hospitalization period were assessed. The time-dependent variables (occurrence of complications) were evaluated with occurrence up through the day before the actual prediction period started. The important prognostic variables for the endpoint death were ventricular fibrillation, age, congestive heart failure, and asystole. Variables for the endpoint cardiac arrest were congestive heart failure, ventricular premature beats, supraventricular tachycardia, extension of MI, and age. Variables for the endpoint cardiogenic shock were cardiac arrest, age, congestive heart failure, previous MI, and nodal rhythm. By using a hazard function for each endpoint and the coefficients for the variables entered, it is possible to estimate a total risk of death, cardiac arrest, or cardiogenic shock for the individual patient. This prediction can be updated during the course of hospitalization according to the occurrence of the new complications. The model can be directly utilized to assess risk.
Authors:
E B Madsen; P Hougaard; E Gilpin
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  51     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1579-83     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Aged
Arrhythmias, Cardiac / etiology
Death
Female
Heart Arrest / etiology
Heart Failure / etiology
Humans
Male
Middle Aged
Myocardial Infarction / complications,  diagnosis*
Prognosis
Risk
Shock, Cardiogenic / etiology
Grant Support
ID/Acronym/Agency:
1 F05 TW0 3154-01/TW/FIC NIH HHS; HL 17682/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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