| Dynamic contrast enhancement of the upper abdomen: effect of contrast medium and body weight. | |
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MedLine Citation:
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PMID: 6618827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Contrast enhancement (CE) of the aorta, liver, and spleen was studied in dynamic body computed tomography (CT) in 71 patients. Four contrast media (CM) (diatrizoate, ioxithalamate, ioxaglate, iopamidol) were injected intravenously in equal bolus doses of 18.5 g iodine. Iopamidol produced the highest average peak and 2-minute aortic CE, significantly different from ioxithalamate (P less than 0.001), diatrizoate (P less than 0.01), and ioxaglate (P less than 0.0125) at peak levels. Two-minute CE values of the aorta were highest with iopamidol as were peak and 2 minute CE of the liver and spleen. A linear, inverse relationship between body weight and CE was present both at peak CE and after 2 minutes in all tissues. The nonionic CM appear to have best dose efficiency in the vascular phase of dynamic CT. These results are also applicable to digital angiography. Differences in the CE of parenchymal organs with different CM are so small that they are unlikely to have clinical significance. |
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Authors:
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M Kormano; K Partanen; S Soimakallio; T Kivimäki |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Investigative radiology Volume: 18 ISSN: 0020-9996 ISO Abbreviation: Invest Radiol Publication Date: 1983 Jul-Aug |
Date Detail:
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Created Date: 1983-11-23 Completed Date: 1983-11-23 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0045377 Medline TA: Invest Radiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 364-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aortography* Body Weight Contrast Media* Diatrizoate / diagnostic use Female Humans Iodobenzoates / diagnostic use* Iopamidol Iothalamic Acid / analogs & derivatives, diagnostic use Ioxaglic Acid Liver / radiography* Male Spleen* / radiography* Tomography, X-Ray Computed Triiodobenzoic Acids / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Iodobenzoates; 0/Triiodobenzoic Acids; 117-96-4/Diatrizoate; 2276-90-6/Iothalamic Acid; 28179-44-4/ioxitalamic acid; 59017-64-0/Ioxaglic Acid; 62883-00-5/Iopamidol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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