| Dynamic contrast-enhanced breast MRI at 7 Tesla utilizing a single-loop coil: a feasibility trial. | |
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MedLine Citation:
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PMID: 20599158 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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RATIONALE AND OBJECTIVES: The aim of this study was to assess the feasibility of dynamic contrast-enhanced ultra-high-field breast imaging at 7 Tesla. MATERIAL AND METHODS: A total of 15 subjects, including 5 patients with histologically proven breast cancer, were examined on a 7 Tesla whole-body magnetic resonance imaging system using a unilateral linearly polarized single-loop coil. Subjects were placed in prone position on a biopsy support system, with the coil placed directly below the region of interest. The examination protocol included the following sequences: 1) T2-weighted turbo spin echo sequence; 2) six dynamic T1-weighted spoiled gradient-echo sequences; and 3) subtraction imaging. RESULTS: Contrast-enhanced T1-weighted imaging at 7 Tesla could be obtained at high spatial resolution with short acquisition times, providing good image accuracy and a conclusively good delineation of small anatomical and pathological structures. T2-weighted imaging could be obtained with high spatial resolution at adequate acquisition times. Because of coil limitations, four high-field magnetic resonance examinations showed decreased diagnostic value. CONCLUSIONS: This first scientific approach of dynamic contrast-enhanced breast magnetic resonance imaging at 7 Tesla demonstrates the complexity of ultra-high-field breast magnetic resonance imaging and countenances the implementation of further advanced bilateral coil concepts to circumvent current limitations from the coil and ultra-high-field magnetic strength. |
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Authors:
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Lale Umutlu; Stefan Maderwald; Oliver Kraff; Jens M Theysohn; Sherko Kuemmel; Elke A Hauth; Michael Forsting; Gerald Antoch; Mark E Ladd; Harald H Quick; Thomas C Lauenstein |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Academic radiology Volume: 17 ISSN: 1878-4046 ISO Abbreviation: Acad Radiol Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-05 Completed Date: 2010-08-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9440159 Medline TA: Acad Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 1050-6 Citation Subset: IM |
Copyright Information:
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2010 AUR. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Germany. Lale.Umutlu@uk-essen.de <Lale.Umutlu@uk-essen.de> |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Breast / pathology* Breast Neoplasms / diagnosis* Contrast Media / diagnostic use Feasibility Studies Female Humans Magnetic Resonance Imaging / instrumentation* Middle Aged Prone Position |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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