| Dynamic characteristics of heart rate control by the autonomic nervous system in rats. | |
| | |
MedLine Citation:
|
PMID: 20511330 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We estimated the transfer function of autonomic heart rate (HR) control by using random binary sympathetic or vagal nerve stimulation in anaesthetized rats. The transfer function from sympathetic stimulation to HR response approximated a second-order, low-pass filter with a lag time (gain, 4.29 +/- 1.55 beats min(1) Hz(1); natural frequency, 0.07 +/- 0.03 Hz; damping coefficient, 1.96 +/- 0.64; and lag time, 0.73 +/- 0.12 s). The transfer function from vagal stimulation to HR response approximated a first-order, low-pass filter with a lag time (gain, 8.84 +/- 4.51 beats min(1) Hz(1); corner frequency, 0.12 +/- 0.06 Hz; and lag time, 0.12 +/- 0.08 s). These results suggest that the dynamic characteristics of HR control by the autonomic nervous system in rats are similar to those of larger mammals. |
| | |
Authors:
|
Masaki Mizuno; Toru Kawada; Atsunori Kamiya; Tadayoshi Miyamoto; Shuji Shimizu; Toshiaki Shishido; Scott A Smith; Masaru Sugimachi |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-28 |
Journal Detail:
|
Title: Experimental physiology Volume: 95 ISSN: 1469-445X ISO Abbreviation: Exp. Physiol. Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-17 Completed Date: 2010-11-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9002940 Medline TA: Exp Physiol Country: England |
Other Details:
|
Languages: eng Pagination: 919-25 Citation Subset: IM |
Affiliation:
|
Departments of Physical Therapy and Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9174, USA. masaki.mizuno@utsouthwestern.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Autonomic Nervous System / physiology* Blood Pressure Electric Stimulation Fourier Analysis Heart / innervation* Heart Rate* Rats Rats, Sprague-Dawley Reaction Time Signal Processing, Computer-Assisted Sympathetic Nervous System / physiology Time Factors Vagus Nerve / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiovascular flashlight. Cardiac pheochromocytoma.
Next Document: Expression of key ion channels in the rat cardiac conduction system by laser capture microdissection...