| Dynamic changes in left ventricular regional wall thickness during premature ventricular contraction in conscious dogs. | |
| | |
MedLine Citation:
|
PMID: 2420728 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The contractile pattern of the regional left ventricular wall during premature ventricular contraction was analyzed in conscious dogs instrumented with an ultrasonic dimension gauge across the anterior and posterior left ventricular walls. Aortic flow was measured with an electromagnetic flow probe. A single premature ventricular contraction was induced by stimulating either the anterior or posterior wall with varied coupling intervals from 380 to 650 msec. Stroke volume of premature ventricular contraction was significantly smaller than that of premature atrial contraction with identical coupling intervals. In premature contractions, stroke volume was linearly related to coupling intervals. Though there was no isovolumic wall thickening in premature atrial contraction, the wall started to thicken during isovolumic ventricular systole in premature ventricular contraction. There was a clear inverse correlation between the ratio of the isovolumic wall thickening to the total wall thickening and coupling intervals. In premature ventricular contractions with identical coupling intervals, the deformation of thickening characteristics was more pronounced in regions with closer proximity to the ectopic focus. Thus it is concluded that the pump function is depressed in premature ventricular contraction, in part due to the increased ratio of wall thickening during isovolumic systole before the opening of the aortic valve. Isovolumic wall thickening increases along with the shorter coupling intervals and closer proximity to the ectopic focus. These alterations in left ventricular mechanical function due to ectopic contraction might induce serious sequelae, depending upon the ectopic focus in the presence of already depressed regional function. |
| | |
Authors:
|
S Sasayama; W N Zhang; Y Kihara; A Ohyagi; J D Lee; G Osakada; C Kawai |
Related Documents
:
|
7900888 - An ultrasonic system for measurement of absolute myocardial thickness using a single tr... 11175178 - Myocardial velocity gradient assessed by a tissue doppler imaging technique. 3098048 - Evaluation of effects of nitroglycerin therapy by echocardiography. 7265458 - Detection of left ventricular asynergy in myocardial infarction by means of ultrasono-c... 12740248 - Frequency, risk factors, and outcome of hyperlactatemia after cardiac surgery. 3966948 - Myocarditis confirmed by biopsy presenting as acute myocardial infarction. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: International journal of cardiology Volume: 10 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 1986 Mar |
Date Detail:
|
Created Date: 1986-05-07 Completed Date: 1986-05-07 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 263-75 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cardiac Complexes, Premature / pathology* Cardiac Pacing, Artificial Cardiac Volume* Dogs Electrocardiography Heart Ventricles / pathology* Hemodynamics Myocardial Contraction Myocardium / pathology Stroke Volume |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Protein phosphorylation at tyrosine residues in v-abl transformed mouse lymphocytes and fibroblasts.
Next Document: Isoprinosine abolishes the blocking factor-mediated inhibition of lymphocyte responses to Epstein-Ba...