Document Detail

Dynamic changes of cerebrospinal fluid in upright and recumbent shunted experimental animals.
MedLine Citation:
PMID:  1183259     Owner:  NLM     Status:  MEDLINE    
The effect of positional change on intracranial CSF pressure, valve flow rates and atrial pressures were studied in 40 experimental dogs. The flow rate with a 30 to 60 mm H2O Holter valve changed from the recumbent to the head-up position: during the first minute it increased 2 1/2 times and then progressively decreased to become stabilized 20-30 min later at a value slightly lower than the head-up value. At the same time pressure dropped rapidly to -23 mm H2O and then slowly, during 30 min to -120 mm H2O. In dogs without a shunt the pressure drop was initially similar to that of shunted dogs but recovered to almost the initial positive pressure in 30 min. The flow rate from a reservoir to the atrium through a shunt system when changing to the head-up position showed a siphon effect. Atrial pressure does not change with positioning. The findings were similar with cisternal-peritoneal shunts. Flow rate, therefore, increase in the head-up position. Negative intracranial CSF pressure was due to a siphon effect through the shunt system.
S Yamada; T B Ducker; P L Perot
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Child's brain     Volume:  1     ISSN:  0302-2803     ISO Abbreviation:  Childs Brain     Publication Date:  1975  
Date Detail:
Created Date:  1976-01-29     Completed Date:  1976-01-29     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7505428     Medline TA:  Childs Brain     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  187-92     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Cerebrospinal Fluid Shunts*
Heart Atria
Intracranial Pressure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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