Document Detail

Dynamic behavior of giant liposomes at desired osmotic pressures.
MedLine Citation:
PMID:  19725557     Owner:  NLM     Status:  MEDLINE    
To apply accurate and uniform osmotic pressures to liposomes, they can be formed using the spontaneous transfer method in solutions with different osmolarities. The majority of liposomes unexpectedly opened large holes (several micrometers in diameter) in response to the osmotic pressure regardless of its strength, that is, the difference between the outside and inside solute (sucrose or KCl) concentrations. However, the lag time for any response, including the opening of a hole, after the formation of the liposome decreased with increasing osmotic pressure.
Masae Ohno; Tsutomu Hamada; Kingo Takiguchi; Michio Homma
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Langmuir : the ACS journal of surfaces and colloids     Volume:  25     ISSN:  0743-7463     ISO Abbreviation:  Langmuir     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-30     Completed Date:  2009-12-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9882736     Medline TA:  Langmuir     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11680-5     Citation Subset:  IM    
Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.
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MeSH Terms
Liposomes / chemistry*
Osmotic Pressure
Potassium Chloride / chemistry
Sucrose / chemistry
Time Factors
Water / chemistry
Reg. No./Substance:
0/Liposomes; 0/Solutions; 57-50-1/Sucrose; 7447-40-7/Potassium Chloride; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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