| Dynamic MR imaging: value of differentiating subtypes of peripheral small adenocarcinoma of the lung. | |
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MedLine Citation:
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PMID: 15489071 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine the utility of dynamic magnetic resonance imaging (MRI) in the differential subtyping of small adenocarcinomas of the lung. MATERIALS AND METHODS: Twenty-nine pathologically diagnosed peripheral adenocarcinomas (less than 20 mm in diameter) underwent dynamic contrast-enhanced MRI. Maximum relative enhancement ratio, slope of enhancement, and corrected start time of enhancement were calculated from signal intensity-time curve of pulmonary lesion for each subject, and were statistically compared among bronchioloalveolar carcinoma (BAC) group (7 cases), mixed BAC group (10 cases), and adenocarcinoma group (12 cases). RESULTS: Maximum relative enhancement ratio (P<0.001) and slope of enhancement (P<0.001) of BAC group were significantly higher than those of mixed BAC and adenocarcinoma groups. Start times of BAC group were significantly earlier than those of mixed BAC (P=0.0001) and adenocarcinoma groups (P<0.0001). Adapting the thresholds values of MR indexes from the positive tests, sensitivity, specificity, positive predictive value, negative predictive value and accuracy for differentiating BAC from other subtypes were 85.7, 100.0, 100.0, 95.7, and 96.6%, respectively. CONCLUSIONS: Dynamic MRI is useful for differentiating subtypes of small peripheral adenocarcinoma. |
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Authors:
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Yoshiharu Ohno; Hiroto Hatabu; Daisuke Takenaka; Hidemasa Uematsu; Chiho Ohbayashi; Takanori Higashino; Munenobu Nogami; Masahiro Yoshimura; Masahiko Fujii; Kazuro Sugimura |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of radiology Volume: 52 ISSN: 0720-048X ISO Abbreviation: Eur J Radiol Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2004-10-18 Completed Date: 2005-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
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Languages: eng Pagination: 144-50 Citation Subset: IM |
Affiliation:
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Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. yosirad@kobe-u.ac.jp <yosirad@kobe-u.ac.jp> |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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classification*,
pathology* Adult Aged Aged, 80 and over Female Humans Lung Neoplasms / classification*, pathology* Magnetic Resonance Imaging* Male Middle Aged |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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