| Dynamic MR imaging of neurohypophyseal germ cell tumors for differential diagnosis of infundibular diseases. | |
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MedLine Citation:
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PMID: 11092476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To investigate the MR dynamic patterns of neurohypophyseal germ cell tumors (GCTs) for differential diagnosis of infundibular diseases affecting young people. MATERIAL AND METHODS: Eleven patients with neurohypophyseal GCTs underwent dynamic MR studies with Tl-weighted spin-echo (SE) or turbo SE techniques. Other infundibular lesions, including adenohypophysitis (n=3), Langerhans' cell histiocytosis (LCH, n=2), and 1 hemangioblastoma from von Hippel-Lindau disease, were also evaluated. Serial images were obtained every 15 s (turbo SE) or 30 s (SE technique) for 240 s after rapid injection of contrast medium. The dynamic patterns were analyzed quantitatively with the contrast medium enhancement ratio. RESULTS: On dynamic MR images, GCTs typically showed a gradual enhancement increase with a peak between 105 s and 180 s, while two showed a relatively rapid increase. LCH and hemangioblastoma showed a dynamic pattern similar to GCTs, while adenohypophysitis demonstrated a sharp rise and a steeper wash-out with an obvious peak before 90 s. CONCLUSION: Typical dynamic pattern of GCTs was the gradual enhancement increase without wash-out. Dynamic MR imaging can distinguish GCTs from adenohypophysitis, but is not useful for differentiation from LCH. |
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Authors:
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L Liang; Y Korogi; T Sugahara; I Ikushima; Y Shigematsu; T Okuda; M Takahashi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 41 ISSN: 0284-1851 ISO Abbreviation: Acta Radiol Publication Date: 2000 Nov |
Date Detail:
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Created Date: 2000-11-27 Completed Date: 2000-12-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 562-6 Citation Subset: IM |
Affiliation:
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Department of Radiology, Kumamoto University School of Medicine. Kumamoto, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Child, Preschool Diagnosis, Differential Female Germinoma / diagnosis* Hemangioblastoma / diagnosis Histiocytosis, Langerhans-Cell / diagnosis Humans Magnetic Resonance Imaging* Male Pituitary Diseases / diagnosis Pituitary Gland, Anterior Pituitary Gland, Posterior* Pituitary Neoplasms / diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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