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Dynamic Contrast-Enhanced MR Imaging for Soft Tissue Sarcomas.
MedLine Citation:
PMID:  11387129     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Dynamic contrast-enhanced magnetic resonance imaging has recently emerged as an important method for evaluating soft tissue sarcomas for biopsy localization, chemotherapeutic response, and long-term follow-up because of its ability to detect viable tumor. This article presents the basic principles of contrast kinetics in soft tissue sarcomas after bolus injection of contrast agent and discusses the current postprocessing methods (subtraction, first-pass image and time-intensity curves with region of interest, and color-encoded techniques) used to display these dynamic studies. Because of its excellent temporal resolution, dynamic MR imaging can delineate the early uptake of contrast agent in sarcomas within seconds after injection, almost synchronous with arterial enhancement, and thereby differentiate the rapidly enhancing viable tumor from the nonenhancing necrotic tumor and the late enhancing changes after surgery, radiation therapy, and chemotherapy.
Authors:
Lorraine G. Shapeero; Daniel Vanel; Koenraad L. Verstraete; Johan L. Bloem
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Seminars in musculoskeletal radiology     Volume:  3     ISSN:  1098-898X     ISO Abbreviation:  Semin Musculoskelet Radiol     Publication Date:  1999  
Date Detail:
Created Date:  2001-Jun-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9717520     Medline TA:  Semin Musculoskelet Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  101-114     Citation Subset:  -    
Affiliation:
Department of Radiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, and Department of Radiology, Walter Reed Army Medical Center, Washington, District of Columbia.
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