| Dynamic CT Perfusion Imaging for the Detection of Crossed Cerebellar Diaschisis in Acute Ischemic Stroke. | |
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MedLine Citation:
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PMID: 22247631 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: Although the detection of crossed cerebellar diaschisis (CCD) by means of different imaging modalities is well described, little is known about its diagnosis by computed tomography perfusion (CTP) imaging. We investigated the detection rate of CCD by CTP imaging and the factors related to CCD on CTP images in patients with acute ischemic stroke. MATERIALS AND METHODS: CT perfusion maps of cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and time-to-peak (TTP) obtained from 81 consecutive patients affected by an acute ischemic stroke were retrospectively reviewed. Whole-brain perfusion maps were obtained with a multichannel CT scanner using the toggling-table technique. The criteria for CCD was a unilateral supratentorial ischemic lesion and an accompanying decrease in perfusion of the contralateral cerebellar hemisphere on the basis of CTP maps by visual inspection without a set threshold. Maps were quantitatively analyzed in CCD positive cases. RESULTS: The criteria for CCD were fulfilled in 25 of the 81 cases (31%). Detection rates per CTP map were as follows: MTT (31%) > TTP (21%) > CBF (9%) > CBV (6%). Supratentorial ischemic volume, degree of perfusion reduction, and infratentorial asymmetry index correlated strongly (R, 0.555-0.870) and significantly (p < 0.05) with each other in CCD-positive cases. CONCLUSION: It is possible to detect CCD on all four of the CTP-based maps. Of these maps, MTT is most sensitive in detecting CCD. Our data indicate that CTP imaging is a valid tool for the diagnosis of CCD in patients affected by an acute hemispheric stroke. |
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Authors:
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Young Wook Jeon; Seo Hyun Kim; Ji Yong Lee; Kum Whang; Myung Soon Kim; Young Ju Kim; Myeong Sub Lee; |
Publication Detail:
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Type: Journal Article Date: 2011-12-23 |
Journal Detail:
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Title: Korean journal of radiology : official journal of the Korean Radiological Society Volume: 13 ISSN: 2005-8330 ISO Abbreviation: Korean J Radiol Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-01-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100956096 Medline TA: Korean J Radiol Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 12-9 Citation Subset: IM |
Affiliation:
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Department of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Gangwon-do 220-701, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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