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Durchsicht der Literatur und Fallbericht eines Patienten mit sklerosierender verkapselnder Peritonitis, der durch parenterale Ernährung zu Hause versorgt wird.
MedLine Citation:
PMID:  22139878     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We present a case of a 48 year old HIV patient, who had recurrent episodes of ascites since 2007. His history includes ischaemic heart disease, for which he was treated with atenolol from 2005 to 2007, and Type 2 diabetes; he was later started on propranolol 40 mg twice a day from 2007 for Didanosine-induced portal hypertension. Because of negative cultures and neutrophil count < 250 cells/μL, spontaneous bacterial peritonitis was excluded. However, some low grade-peritoneal irritation cannot be ruled out because his CRP varied from 24 to 258, during 2007 - 2009, without any other obvious inflammatory cause. He was finally diagnosed in July 2009 with sclerosing encapsulating peritonitis (SEP) based on clinical features of intestinal obstruction, histology and imaging, including computed tomography and magnetic resonance imaging. Propranolol was stopped in November 2009. Because of the patient's severe intestinal obstruction, he was started on parenteral nutrition 2 L/day. Since then, his CRP has returned to normal levels and there is a great improvement of his clinical features. This case demonstrates beta-blockers as a potential cause of SEP, while the presence of some low-grade peritoneal inflammation leading to SEP is also very likely.
Authors:
K C Fragkos; F M Al-Sulttan; R P Mookerjee; A Winstanley; A Forbes
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Publication Detail:
Type:  Journal Article     Date:  2011-12-02
Journal Detail:
Title:  Zeitschrift für Gastroenterologie     Volume:  49     ISSN:  1439-7803     ISO Abbreviation:  Z Gastroenterol     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-12-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0033370     Medline TA:  Z Gastroenterol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1543-8     Citation Subset:  IM    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Department of Histopathology, University College London Hospital.
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