Document Detail

Duration of postictal psychotic episodes.
MedLine Citation:
PMID:  17386048     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To clarify duration of postictal psychosis (PIP) episodes and identify factors that influence its duration. METHODS: Fifty-eight patients with epilepsy exhibited 151 PIP episodes during a mean follow-up period of 12.8 years. Distribution of the duration of these episodes was determined, and factors potentially affecting were analyzed. Factors analyzed included PIP-related variables (i.e., antecedent seizures and the lucid interval) and patient characteristics (i.e., type of epilepsy, lateralization of EEG abnormalities, and intellectual functioning). RESULTS: The mean duration of the 58 first PIP episodes was 10.5 days, and that of all 151 PIP episodes (including multiple episodes) was 9.2 days. Approximately 95% of the PIP episodes resolved within 1 month. Most PIP-related variables, except for antipsychotic drugs administered, were not associated with duration of the episodes. Several patient characteristics, i.e., history of interictal psychosis, family history of psychosis, and intellectual functioning, were associated with duration of the PIP episodes. CONCLUSIONS: This study showed that most PIP episodes last less than 1 month. PIP episodes appear to be prolonged when individuals have an underlying vulnerability to psychosis. Clinical phenomena that can trigger PIP may not determine the course of the PIP episode.
Naoto Adachi; Masumi Ito; Kousuke Kanemoto; Nozomi Akanuma; Mitsutoshi Okazaki; Shiro Ishida; Masanori Sekimoto; Masaaki Kato; Jun Kawasaki; Yukari Tadokoro; Tomonori Oshima; Teiichi Onuma
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-03-26
Journal Detail:
Title:  Epilepsia     Volume:  48     ISSN:  0013-9580     ISO Abbreviation:  Epilepsia     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-13     Completed Date:  2007-09-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1531-7     Citation Subset:  IM    
Adachi Mental Clinic, Kitano 7-5-12, Kiyota, Sapporo 004-0867, Japan.
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MeSH Terms
Age of Onset
Antipsychotic Agents / therapeutic use
Cerebral Cortex / physiopathology
Electroencephalography / statistics & numerical data
Epilepsy / complications*,  physiopathology,  psychology
Factor Analysis, Statistical
Follow-Up Studies
Functional Laterality
International Classification of Diseases / statistics & numerical data
Longitudinal Studies
Middle Aged
Psychiatric Status Rating Scales / statistics & numerical data
Psychotic Disorders / diagnosis*,  etiology*,  psychology
Time Factors
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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