| Duration of human chorionic gonadotropin surveillance for partial hydatidiform moles. | |
| | |
MedLine Citation:
|
PMID: 15902109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Partial hydatidiform moles infrequently progress to gestational trophoblastic neoplasia. The purpose of this study was to determine the optimal duration of human chorionic gonadotropin surveillance. STUDY DESIGN: We retrospectively reviewed the clinical follow-up of all women who were diagnosed with partial hydatidiform mole at our institution from 1983 to 2003. RESULTS: One hundred sixty-three patients were identified with a median age of 23 years (range, 14-42 years). Seventy-four patients (45%) attained undetectable levels of human chorionic gonadotropin; none of the patients had gestational trophoblastic neoplasia. Forty patients completed the 6 months of recommended follow-up; 6 patients conceived during surveillance, and 28 patients did not return for any further office visits 1 to 5 months after achieving remission. Eighty-three patients (51%) were lost to follow-up before normalization of human chorionic gonadotropin. Six women (4%) had stage I gestational trophoblastic neoplasia during surveillance. CONCLUSION: Our results support the suggestion that a single undetectable human chorionic gonadotropin level after evacuation is sufficient follow-up to ensure remission in patients with partial hydatidiform moles. |
| | |
Authors:
|
Isaac Lavie; Gautam G Rao; Diego H Castrillon; David S Miller; John O Schorge |
Related Documents
:
|
2638719 - Acute appendicitis in singapore children--some clinical aspects. 21144219 - High prevalence of humoral immunodeficiency patients with refractory chronic rhinosinus... 7338159 - Ovulatory dysfunction in patients with endometriosis. 8671229 - Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and... 19491419 - Chronology of meiosis & synaptonemal complex abnormalities in normal & abnormal spermat... 21993669 - Evidence for a role of anti-adamts13 autoantibodies despite normal adamts13 activity in... 17594749 - Hypercalciuria associated with pediatric prostatic calculi. 22791199 - Simultaneous carotid endarterectomy and cardiac surgery: early results of 386 patients. 16154679 - Reducing no flow times during automated external defibrillation. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 192 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2005 May |
Date Detail:
|
Created Date: 2005-05-19 Completed Date: 2005-06-24 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 1362-4 Citation Subset: AIM; IM |
Affiliation:
|
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75390-9032, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Chorionic Gonadotropin / blood* Female Gestational Trophoblastic Neoplasms / blood, diagnosis, epidemiology, pathology Humans Hydatidiform Mole / blood*, surgery Incidence Neoplasm Staging Population Surveillance* Postoperative Period Pregnancy Retrospective Studies Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Chorionic Gonadotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Elevated first-trimester nuchal translucency increases the risk of congenital heart defects.
Next Document: Carboplatin and paclitaxel for the treatment of advanced or recurrent endometrial cancer.