Document Detail


Duration of head-up tilt test for patients with suspected vasovagal syncope.
MedLine Citation:
PMID:  21357590     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: To investigate the appropriate duration of head-up tilt test (HUTT) needed to induce a positive reaction in patients with suspected vasovagal syncope.
METHODS AND RESULTS: Consecutive patients referred to the syncope unit of our centre for recurrent unexplained syncope were studied. The HUTT included a 30 min passive basic phase and a 20 min sublingual nitroglycerin provocation phase if syncope did not develop during the passive phase. We studied 773 consecutive patients, and 427 (55.2%) patients had a positive HUTT, including 46 patients (10.8%) during the passive basic phase and 381 patients (89.2%) during the nitroglycerin provocation phase. During the basic phase, positive reaction appeared at 7.5 min, and the percentage of positive cases increased with the duration of the test, reaching a peak (20.9%) at 22.5 min, and then decreasing gradually. Most positive reactions (96.1%) occurred between 10 and 25 min during the basic phase. During the nitroglycerin provocation phase, however, the percentage of positive reactions increased rapidly after sublingual nitroglycerin, peaking (35.7%) at 10 min, followed by a sharp decline. Most positive reactions (96.1%) occurred in the first 15 min of the provocation phase.
CONCLUSION: The HUTT was a useful diagnostic test in patients with suspected vasovagal syncope, and sublingual nitroglycerin increased the rate of positive reactions. The appropriate duration for HUTT required at least 25 min during the passive basic phase and 15 min during the nitroglycerin provocation phase.
Authors:
Jun Liu; Pihua Fang; Yue Liu; Guoying Lu; Zhi Li; Xiaofeng Li; Yushan Wang
Publication Detail:
Type:  Journal Article     Date:  2011-02-25
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  13     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-30     Completed Date:  2011-08-11     Revised Date:  2011-12-23    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  576-80     Citation Subset:  IM    
Affiliation:
Cardiac Function Test Center, Peking Union Medical College and Chinese Academy of Medical Sciences, 167 North Lishi Road, Xicheng State, Beijing, 100037 China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Female
Humans
Male
Middle Aged
Nitroglycerin / diagnostic use
Retrospective Studies
Syncope, Vasovagal / diagnosis*,  physiopathology*
Tilt-Table Test / methods*
Time Factors
Vasodilator Agents / diagnostic use
Young Adult
Chemical
Reg. No./Substance:
0/Vasodilator Agents; 55-63-0/Nitroglycerin
Comments/Corrections
Comment In:
Europace. 2011 Dec;13(12):1802   [PMID:  21712268 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults.
Next Document:  The diagnostic performance of scoring systems to identify symptomatic colorectal cancer compared to ...