Document Detail

Durable Hydrophilic Microchannels with Controlled Morphology by the Direct Molding Method.
MedLine Citation:
PMID:  21348437     Owner:  NLM     Status:  Publisher    
We present a laminated hydrophilic microchannel fabricated by a direct micromolding and facile bonding technique with a hydrophilic organic-inorganic hybrid (HP) resin, which is built into two supporting parallel polydimethylsiloxane (PDMS) substrates. This approach allows one to shape the cross-section of the hydrophilic channel into a regular rectangular or geometrically complicated mouth-throat structure. Spontaneous self-wetting flow of water occurs when water is introduced to the HP microchannel with rectangular cross-section without the aid of mechanical pumping or electric field. The capillary flow velocity can be controlled by varying the channel size. The channel surface behaves like a glass surface in terms of zeta potential for pH larger than 3, and the electro-osmotic flow (EOF) velocity can be as high as 4.7 × 10(-4) cm(2)/V·sec at pH 9.0. The capillary electrophoresis (CE) module made of the HP resin for amino acid or DNA separation is demonstrated to yield a higher resolution in a shorter retention time with repeatability and long-lasting durable performance with antifouling property, when compared with PDMS CE.
Tae-Ho Yoon; Ming Li; Lan-Young Hong; Jinkee Lee; Dong-Pyo Kim
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-24
Journal Detail:
Title:  Analytical chemistry     Volume:  -     ISSN:  1520-6882     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370536     Medline TA:  Anal Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Center of Applied Microfluidic Chemistry and ∥Graduate School of Analytical Science and Technology, Chungnam National University , Daejeon, 305-764, South Korea.
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