| Durability of antireflux effect of ureteral reimplantation for primary vesicoureteral reflux: findings on long-term cystography. | |
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MedLine Citation:
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PMID: 22245304 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the long-term durability of successful ureteral reimplantation (UR) for vesicoureteral reflux (VUR) through a review of late cystography (LC) findings. MATERIALS AND METHODS: We performed a retrospective chart review of all children with primary VUR who underwent successful open UR (grade 0 VUR into the reimplanted ureter[s] on initial cystogram) at our institution from January 1990 to December 2002. We identified successful UR patients who underwent LC ≥ 1 year after UR and reviewed the results for the presence of recurrent VUR into the reimplanted ureter(s). RESULTS: Seven-hundred ninety-four patients underwent successful open UR for primary VUR, of whom 60 (7.6%) had a subsequent LC. Preoperative VUR grade was ≤ II in 20 (34.5%) and ≥ III in 38 (65.5%). Median age at UR was 3.5 years (IQR 1.3-6.2 years); 51 (85%) were female. UR was intravesical in 45 (75%) and bilateral in 19 (32%). LC was performed at a median of 38.7 months after UR (IQR 19.6-66.1 months). Indication for LC was febrile urinary tract infection (UTI) in 16 (27%), nonfebrile UTIs in 15 (25%), follow-up of contralateral VUR in 16 (27%), and other clinical indications in 13 (21%). The recurrence rate was 0%; of the 79 reimplanted ureters, 100% (95% CI 95.4-100) had no VUR (grade 0). CONCLUSION: Among children who underwent successful open UR for primary VUR, there was no VUR recurrence on extended follow-up. This suggests that the late durability of open antireflux surgery is excellent. |
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Authors:
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Katherine C Hubert; Paul J Kokorowski; Lin Huang; Michaella M Prasad; Ilina Rosoklija; Alan B Retik; Caleb P Nelson |
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Publication Detail:
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Type: Journal Article; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S. Date: 2012-01-13 |
Journal Detail:
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Title: Urology Volume: 79 ISSN: 1527-9995 ISO Abbreviation: Urology Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-03-05 Completed Date: 2012-05-18 Revised Date: 2012-12-07 |
Medline Journal Info:
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Nlm Unique ID: 0366151 Medline TA: Urology Country: United States |
Other Details:
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Languages: eng Pagination: 675-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Urology, Children's Hospital Boston, Boston, MA 02115, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child Child, Preschool Female Humans Infant Male Recurrence Replantation Retrospective Studies Treatment Outcome Ureter / radiography, surgery* Urinary Tract Infections / etiology Urologic Surgical Procedures / methods* Vesico-Ureteral Reflux / complications, radiography, surgery* |
| Grant Support | |
ID/Acronym/Agency:
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K23-DK088943/DK/NIDDK NIH HHS; T32-DK60442/DK/NIDDK NIH HHS; T32-HS19485/HS/AHRQ HHS |
| Comments/Corrections | |
Comment In:
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J Urol. 2012 Nov;188(5):1941
[PMID:
23059249
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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