Document Detail


Duplication 3p21----3pter and cyclopia.
MedLine Citation:
PMID:  3605204     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on a patient with an interchromosomal duplication of 3p, from 3p21 to 3pter, which apparently arose de novo. The infant had multiple malformations including holoprosencephaly and cyclopia. It is possible that duplication 3p has a generalized effect on the holoprosencephalon or the cleavage of the embryonic forebrain. Fibroblasts from the patient are available from the NIGMS Human Genetic Mutant Cell Repository (GM 7216).
Authors:
D N Kurtzman; D L Van Dyke; C A Rich; L Weiss
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  27     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-07-24     Completed Date:  1987-07-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  33-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics*
Brain / abnormalities*
Chromosome Aberrations*
Chromosomes, Human, Pair 3*
Female
Humans
Infant, Newborn
Orbit / abnormalities*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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