Document Detail

Duplex criteria for in-stent restenosis in the superficial femoral artery.
MedLine Citation:
PMID:  22639187     Owner:  NLM     Status:  Publisher    
OBJECTIVES: To elucidate the optimal cut-off and accuracy of duplex ultrasonography (DUS) parameters for in-stent restenosis (ISR) after nitinol stenting in the superficial femoral artery (SFA). BACKGROUND: Few data are available regarding the performance of DUS for binary ISR based on quantitative vessel analysis (QVA) in the era of SFA nitinol stenting. METHODS: This retrospective study included a total of 74 in-stent stenoses of SFA who underwent DUS before follow-up angiography. DUS parameters, such as peak systolic velocity (PSV) and the peak systolic velocity ratio (PSVR), were compared with percent diameter stenosis (%DS) from a QVA basis. RESULTS: There was a statistically significant correlation (P <0.001) between "%DS and PSV" and "%DS and PSVR", and the correlation with %DS proved to be stronger in PSVR (R=0.720) than in PSV (R=0.672). The best performing parameter for ISR (50% or greater stenosis) was revealed to be PSVR, as the areas under the receiver operator characteristics curves using PSVR and PSV were 0.908 and 0.832, respectively. A PSVR cut-off value of 2.85 yielded the best predictive value with sensitivity of 88%, specificity of 84%, and accuracy of 86%. The positive predictive value was 85% and the negative predictive value was 88%. CONCLUSIONS: A PSVR of 2.85 is the optimal threshold for ISR after nitinol stenting in the SFA. Further large prospective studies are required for the validation and establishment of uniform criteria for DUS parameters. © 2012 Wiley Periodicals, Inc.
Osami Kawarada; Akihiro Higashimori; Miyuki Noguchi; Naoto Waratani; Masafumi Yoshida; Masahiko Fujihara; Yoshiaki Yokoi; Yasuhiro Honda; Peter J Fitzgerald
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-28
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  -     ISSN:  1522-726X     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Nara Nishinokyo Vascular Institute, Department of Cardiovascular Medicine, Nishinokyo Hospital, 102-1, Rokujou, Nara-city, Nara, 630-8041, Japan; Division of Cardiovascular Medicine, Stanford University Medical Center, 300 Pasteur Drive, Room H 3554, Stanford, CA 94305-5637, USA.
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