| Duodeno-jejunal junction dyssynergia: description of a novel syndrome. | |
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MedLine Citation:
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PMID: 17696232 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To investigate the hypothesis that duodeno-jejunal dyssynergia existed at the duodeno-jejunal junction. METHODS: Of 112 patients who complained of epigastric distension and discomfort after meals, we encountered nine patients in whom the duodeno-jejunal junction did not open on duodenal contraction. Seven healthy volunteers were included in the study. A condom which was inserted into the 1st duodenum was filled up to 10 mL with saline in increments of 2 mL and pressure response to duodenal distension was recorded from the duodenum, duodeno-jejunal junction and the jejunum. RESULTS: In healthy volunteers, duodenal distension with 2 and 4 mL did not produce pressure changes, while 6 and up to 10 mL distension effected significant duodenal pressure increase, duodeno-jejunal junction pressure decrease but no jejunal pressure change. In patients, resting pressure and duodeno-jejunal junction and jejunal pressure response to 2 and 4 mL duodenal distension were similar to those of healthy volunteers. Six and up to 10 mL 1st duodenal distension produced significant duodenal and duodeno-jejunal junction pressure increase and no jejunal pressure change. CONCLUSION: Duodeno-jejunal junction failed to open on duodenal contraction, a condition we call 'duodeno-jejunal junction dyssynergia syndrome' which probably leads to stagnation of chyme in the duodenum and explains patients' manifestations. |
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Authors:
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Ahmed Shafik; Ismail A Shafik; Olfat El Sibai; Ali A Shafik |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 13 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-08-16 Completed Date: 2007-11-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 4112-6 Citation Subset: IM |
Affiliation:
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Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo, Egypt. shafik@ahmedshafik.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ataxia / diagnosis, physiopathology* Case-Control Studies Duodenal Diseases / diagnosis, physiopathology Duodenum / physiopathology* Female Gastrointestinal Diseases / diagnosis, physiopathology Gastrointestinal Motility / physiology* Humans Jejunal Diseases / diagnosis, physiopathology Jejunum / physiopathology* Male Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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