| Duodenal ulcer in the elderly. | |
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MedLine Citation:
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PMID: 2794428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Of 333 duodenal ulcer (DU) patients 75 (22.5%) were aged 65-93 years (study group). Ninety-two percent (306 patients) of the entire group were diagnosed endoscopically, and all were followed prospectively. In the study group of the older patients there were fewer smokers, but more patients used steroids and other nonsteroidal antiinflammatory drugs (NSAIDs) and had more arteriosclerotic heart disease than the younger control group. Presenting signs and symptoms were similar in both age groups, although painless upper gastrointestinal bleeding was more common in the elderly, and pain, when present, tended to be milder. Bleeding episodes were more prevalent in the older age group. Another difference between the groups was the larger incidence of concurrent gastric ulcer and DU observed endoscopically in the study population. Steroids and NSAIDs could be etiologically connected to bleeding in the older patients, as well as to their relative lack of pain. We conclude that DU in the elderly tended to present atypically and that pain was not the major symptom of activity. This places a different emphasis on diagnostic and therapeutic criteria. |
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Authors:
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E Scapa; M Horowitz; M Waron; J Eshchar |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of clinical gastroenterology Volume: 11 ISSN: 0192-0790 ISO Abbreviation: J. Clin. Gastroenterol. Publication Date: 1989 Oct |
Date Detail:
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Created Date: 1989-11-07 Completed Date: 1989-11-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7910017 Medline TA: J Clin Gastroenterol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 502-6 Citation Subset: IM |
Affiliation:
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Institute of Gastroenterology, Assaf Harofeh Medical Center, Zerifin, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Anti-Inflammatory Agents / adverse effects Anti-Inflammatory Agents, Non-Steroidal / adverse effects Duodenal Ulcer / diagnosis*, etiology Duodenoscopy Female Humans Male Middle Aged Peptic Ulcer Hemorrhage / etiology Prospective Studies Smoking / adverse effects Steroids Stomach Ulcer / diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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