Document Detail

Duodenal ulcer in the elderly.
MedLine Citation:
PMID:  2794428     Owner:  NLM     Status:  MEDLINE    
Of 333 duodenal ulcer (DU) patients 75 (22.5%) were aged 65-93 years (study group). Ninety-two percent (306 patients) of the entire group were diagnosed endoscopically, and all were followed prospectively. In the study group of the older patients there were fewer smokers, but more patients used steroids and other nonsteroidal antiinflammatory drugs (NSAIDs) and had more arteriosclerotic heart disease than the younger control group. Presenting signs and symptoms were similar in both age groups, although painless upper gastrointestinal bleeding was more common in the elderly, and pain, when present, tended to be milder. Bleeding episodes were more prevalent in the older age group. Another difference between the groups was the larger incidence of concurrent gastric ulcer and DU observed endoscopically in the study population. Steroids and NSAIDs could be etiologically connected to bleeding in the older patients, as well as to their relative lack of pain. We conclude that DU in the elderly tended to present atypically and that pain was not the major symptom of activity. This places a different emphasis on diagnostic and therapeutic criteria.
E Scapa; M Horowitz; M Waron; J Eshchar
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  11     ISSN:  0192-0790     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-11-07     Completed Date:  1989-11-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  502-6     Citation Subset:  IM    
Institute of Gastroenterology, Assaf Harofeh Medical Center, Zerifin, Israel.
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MeSH Terms
Aged, 80 and over
Anti-Inflammatory Agents / adverse effects
Anti-Inflammatory Agents, Non-Steroidal / adverse effects
Duodenal Ulcer / diagnosis*,  etiology
Middle Aged
Peptic Ulcer Hemorrhage / etiology
Prospective Studies
Smoking / adverse effects
Stomach Ulcer / diagnosis
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Steroids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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