Document Detail

Duodenal bile acids in infants with protracted diarrhoea.
MedLine Citation:
PMID:  434889     Owner:  NLM     Status:  MEDLINE    
Bile acids were estimated in the duodenum of infants with protracted diarrhoea and compared with those in a control group. Significantly lower levels of total bile acids were found in infants with protracted diarrhoea, a finding which may be due to ileal dysfunction. Low concentrations of total bile acids may contribute to the poor nutritional state of these patients by impairing the normal digestion and absorption of dietary fat and fat-soluble vitamins. The absence of deconjugated bile acids in the duodenal juice of most infants with protracted diarrhoea suggests that they do not contribute significantly to the pathophysiology of this disorder.
D N Challacombe; G A Brown; S Edkins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  54     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1979 Feb 
Date Detail:
Created Date:  1979-06-11     Completed Date:  1979-06-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  131-4     Citation Subset:  AIM; IM    
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MeSH Terms
Bile Acids and Salts / metabolism*
Diarrhea, Infantile / metabolism*
Duodenum / metabolism*
Ileum / metabolism
Infant, Newborn
Intestinal Secretions / metabolism*
Reg. No./Substance:
0/Bile Acids and Salts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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