Document Detail

Duodenal G- and D-cell changes following corticosteroid administration. Immunocytochemical long-term study in guinea pigs.
MedLine Citation:
PMID:  3573678     Owner:  NLM     Status:  MEDLINE    
Prednisolone administration in guinea pigs for 20 days induces significant hypergastrinemia and duodenal G-cell hyperplasia. Hypergastrinemia and duodenal G-cell hyperplasia are less prominent following 40 days of prednisolone administration and this could be partly attributed to the duodenal D-cell increased activity, which represents an adaptive response to the alterations of gastric secretory functions induced by corticosteroids.
E Xynos; J Vassilakis; K Aroni; C Kittas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  65     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-05-28     Completed Date:  1987-05-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  110-2     Citation Subset:  IM    
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MeSH Terms
Duodenum / drug effects*
Gastrins / blood*
Guinea Pigs
Intestinal Mucosa / drug effects*
Prednisolone / toxicity*
Time Factors
Reg. No./Substance:
0/Gastrins; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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