| The Duett closure device: concept and experimental results. | |
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MedLine Citation:
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PMID: 10652674 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Purpose of this paper is to investigate the hemostatic capabilities of a novel vascular sealing device consisting of a balloon catheter and procoagulant. Vascular sheaths were placed percutaneously in the femoral arteries of dogs. The sealing device was evaluated using the balloon catheter alone in 6 femoral arteries and with the addition of a procoagulant in 21 femoral arteries. The balloon catheter alone was successfully deployed in 6 of 6 femoral arteries achieving immediate hemostasis. In a second study in which the procoagulant was delivered following balloon placement, the sealing device was successfully deployed and hemostasis was achieved in 20 of 21 attempts (95%) despite removal of the balloon catheter. In a subset of fully anticoagulated animals, hemostasis was achieved in the sealing device-treated arteries at 6.5 +/- 3.4 minutes but in none of the controls (p < 0.001). This novel vascular sealing device successfully achieves rapid hemostasis in normal and anticoagulated dogs following percutaneous vascular procedures. |
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Authors:
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G Gershony; T Jensen |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Herz Volume: 24 ISSN: 0340-9937 ISO Abbreviation: Herz Publication Date: 1999 Dec |
Date Detail:
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Created Date: 2000-02-18 Completed Date: 2000-02-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7801231 Medline TA: Herz Country: GERMANY |
Other Details:
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Languages: eng Pagination: 614-9 Citation Subset: IM |
Affiliation:
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John Muir Medical Center, Walnut Creek, California, USA. ggershony@vascularsolutions.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anticoagulants / administration & dosage Balloon Dilatation / instrumentation* Clinical Trials as Topic Collagen / administration & dosage Data Interpretation, Statistical Dogs Femoral Artery Follow-Up Studies Hemostatic Techniques / instrumentation* Hemostatics / administration & dosage Heparin / administration & dosage Humans Punctures / instrumentation* Thrombin / administration & dosage Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Hemostatics; 9005-49-6/Heparin; 9007-34-5/Collagen; EC 3.4.21.5/Thrombin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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