Document Detail


Duchenne muscular dystrophy: negative scotopic bright-flash electroretinogram and normal dark adaptation.
MedLine Citation:
PMID:  7834567     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent reports indicate that most subjects with Duchenne muscular dystrophy (DMD) have a negative scotopic bright-flash electroretinogram (ERG). We performed dark adaptometry in seven patients with the DMD phenotype. Three patients had the negative bright-flash response combined with severely reduced rod-related activity; their mean psychophysical dark-adapted threshold was -5.5 +/- 0.3 (normally -5.4 +/- 0.3) cd.m-2. Two of the three patients were able to sit through the complete test: the profile of their dark adaptation curve was normal. The four other patients had a normal scotopic ERG, and their mean psychophysical dark-adapted threshold was -5.3 +/- 0.3 cd.m-2. One of the four was able to complete the entire procedure, and a normal profile was found. In patients with DMD the dark adaptation measurements are normal despite abnormalities in rod-related ERG activity.
Authors:
F Tremblay; I De Becker; D C Riddell; J M Dooley
Related Documents :
22403017 - Urinary aasa excretion is elevated in patients with molybdenum cofactor deficiency and ...
9508247 - Angelman syndrome without detectable chromosome 15q11-13 anomaly: clinical study of fam...
12368987 - Screening for adenylosuccinate lyase deficiency: clinical, biochemical and molecular fi...
8972767 - A case of type i gaucher disease with cardiopulmonary amyloidosis and chitotriosidase d...
2301257 - Lack of correlation between transient myocardial ischemia and late potentials on the si...
3612267 - C-reactive protein levels in the differential diagnosis of brain abscesses.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  29     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-02-28     Completed Date:  1995-02-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  280-3     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Dalhousie University, Halifax, NS.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Dark Adaptation / physiology*
Electroretinography
Humans
Muscular Dystrophies / physiopathology*
Photic Stimulation
Retinal Rod Photoreceptor Cells / physiology*
Sensory Thresholds / physiology
Visual Perception / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Duchenne muscular dystrophy: negative scotopic bright-flash electroretinogram but not congenital sta...
Next Document:  Anterior transposition of the inferior oblique for dissociated vertical deviation with inferior obli...