Document Detail

Dual-step prospective ECG-triggered 128-slice dual-source CT for evaluation of coronary arteries and cardiac function without heart rate control: a technical note.
MedLine Citation:
PMID:  20407896     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To describe prospective ECG-triggered dual-source CT dual-step pulsing (pECG(dual_step)) for evaluation of coronary arteries and cardiac function.
METHODS: Fifty-one consecutive patients pre- or post-cardiovascular surgery were examined with adaptive sequential tube current modulated (pECG(dual-step)) 128-slice dual-source CT without heart rate control (main padding window: 40% RR interval >65 bpm/70% RR interval <65 bpm). Image quality of coronary arteries was graded (4-point scale), and cardiac function was evaluated.
RESULTS: Mean HR was 68 bpm. Thirty-seven patients were in stable sinus rhythm (SR); 14 had arrhythmia. Image quality of coronary arteries was diagnostic in 804/816 (98%) of segments. The number of non-diagnostic segments was higher in patients with arrhythmia as compared to those in SR (4% vs. 0.5%; p = 0.01), and there were fewer segments with excellent image quality (79% vs. 94%; p < 0.001) and more segments with impaired image quality (p < 0.001 and p = 0.002). Global and regional LV function could be evaluated in 41 (80%) and 47 (92%) patients, and valvular function in 48 (94%). In 11/14 of patients with arrhythmia, the second step switched to full mAs, increasing radiation exposure to 8.6 mAs (p < 0.001). The average radiation dose was 3.8 mSv (range, 1.7-7.9) in patients in SR.
CONCLUSION: pECG(dual-step)128-slice DSCT is feasible for the evaluation of coronary arteries and cardiac function without heart rate control in patients in stable sinus rhythm at a low radiation dose.
Gudrun Feuchtner; Robert Goetti; Andrè Plass; Stephan Baumueller; Paul Stolzmann; Hans Scheffel; Monika Wieser; Borut Marincek; Hatem Alkadhi; Sebastian Leschka
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Publication Detail:
Type:  Journal Article     Date:  2010-04-21
Journal Detail:
Title:  European radiology     Volume:  20     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-03     Completed Date:  2011-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2092-9     Citation Subset:  IM    
Institute of Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland.
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MeSH Terms
Aged, 80 and over
Cardiac-Gated Imaging Techniques / methods*
Coronary Angiography / methods*
Coronary Artery Disease / complications*,  radiography*
Feasibility Studies
Heart Rate
Middle Aged
Radiographic Image Enhancement / methods
Radiographic Image Interpretation, Computer-Assisted / methods
Radiography, Dual-Energy Scanned Projection / methods
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*
Ventricular Dysfunction, Left / etiology*,  radiography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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