Document Detail

Dual-source dual-energy computed tomography angiography for active gastrointestinal bleeding: a preliminary study.
MedLine Citation:
PMID:  22999524     Owner:  NLM     Status:  MEDLINE    
AIM: To assess the utility of dual-source dual-energy computed tomography angiography (DSDECTA) in the diagnosis of active gastrointestinal bleeding (GIB).
MATERIALS AND METHODS: From June 2010 to September 2011, 58 consecutive patients with clinical signs of active GIB underwent DSDECTA. Two radiologists, blinded to clinical data, interpreted images from DSDECTA independently, with discordant interpretation resolved by consensus. The standards of reference included digital subtraction angiography, endoscopy, surgery, or final pathology reports. Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values, and accuracy of DSDECTA for detection of active GIB were evaluated. Receiver-operating characteristic (ROC) analysis was undertaken and the area under the curve (AUC) calculated.
RESULTS: Active GIB source was identified in 39 of 58 patients (67.2%), all of which were confirmed by one or more reference standard. Negative DSDECTA results were obtained in 19 patients (32.8%). Of these, 15 patients did not require any further intervention and were discharged without incident. The overall sensitivity, specificity, PPV, NPV, and accuracy of DSDECTA was 88.6, 100, 100, 73.7, and 91.4%, respectively. The AUC was 0.935 ± 0.063. The dose reduction of a dual-phase DSDECTA protocol was approximately 30%, compared with that of a triple-phase protocol used in a previous study.
CONCLUSION: DSDECTA can act as an accurate method for detection and localization of active GIB and has a relatively low radiation dose.
H Sun; H-D Xue; Y-N Wang; J-M Qian; J-C Yu; F Zhu; H-D Zhu; Z-Y Jin; X-G Li
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Publication Detail:
Type:  Journal Article     Date:  2012-09-21
Journal Detail:
Title:  Clinical radiology     Volume:  68     ISSN:  1365-229X     ISO Abbreviation:  Clin Radiol     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-14     Completed Date:  2013-03-14     Revised Date:  2014-01-31    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  139-47     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
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MeSH Terms
Acute Disease
Aged, 80 and over
Angiography / methods*
Cohort Studies
Gastrointestinal Hemorrhage / pathology,  radiography*,  surgery
Middle Aged
Observer Variation
Prospective Studies
ROC Curve
Radiation Dosage
Radiographic Image Interpretation, Computer-Assisted
Radiography, Dual-Energy Scanned Projection / methods*
Reference Standards
Reproducibility of Results
Severity of Illness Index
Tomography, X-Ray Computed / methods
Young Adult
Comment In:
Rofo. 2013 Sep;184(10):922   [PMID:  24218682 ]
Rofo. 2013 Oct;185(10):922

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