Document Detail

Dual-source CT for visualization of the coronary arteries in heart transplant patients with high heart rates.
MedLine Citation:
PMID:  18647916     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to evaluate the quality of dual-source CT images of the coronary arteries in heart transplant recipients with high heart rates. SUBJECTS AND METHODS: Contrast-enhanced dual-source CT coronary angiography was performed on 23 heart transplant recipients (20 men, three women; mean age, 61.1 +/- 12.8 years). Data sets were reconstructed in 5% steps from 30% to 80% of the R-R interval. Two blinded independent readers using a 5-point scale (0, not evaluative; 4, excellent quality) assessed the quality of images of coronary segments. RESULTS: The mean heart rate during scanning was 89.2 +/- 10.4 beats/min. Interobserver agreement on the quality of images of the whole coronary tree was a kappa value of 0.78 and for selection of the optimal reconstruction interval was a kappa value of 0.82. The optimal reconstruction interval was systole in 17 (74%) of the 23 of heart transplant recipients. At the best reconstruction interval, diagnostic image quality (score >or= 2) was obtained in 92.1% (303 of 329) of the coronary artery segments. The mean image quality score for the whole coronary tree was 3.1 +/- 1.01. No significant correlation between mean heart rate (rho = 0.31) or heart rate variability (rho = 0.23) and overall image quality score was observed (p = not significant). CONCLUSION: Dual-source CT acquisition yields coronary angiograms of diagnostic quality in heart transplant recipients. Mean heart rate and heart rate variability during scanning do not have a negative effect on the overall quality of images of the coronary arteries.
Gorka Bastarrika; Carlo Nicola De Cecco; Maria Arraiza; Stefano Mastrobuoni; Jesús C Pueyo; Matias Ubilla; Gregorio Rábago
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  191     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-23     Completed Date:  2008-08-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  448-54     Citation Subset:  AIM; IM    
Department of Radiology, Clínica Universitaria, Universidad de Navarra, Ave. Pío XII, 36, 31008 Pamplona, Spain.
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MeSH Terms
Contrast Media
Coronary Angiography / methods*
Heart Rate / physiology*
Heart Transplantation*
Iopamidol / analogs & derivatives,  diagnostic use
Middle Aged
Radiographic Image Interpretation, Computer-Assisted
Retrospective Studies
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media; 62883-00-5/Iopamidol; 78649-41-9/iomeprol

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