Document Detail


Dual-process action of exercise on appetite control: increase in orexigenic drive but improvement in meal-induced satiety.
MedLine Citation:
PMID:  19675105     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Exercise could contribute to weight loss by altering the sensitivity of the appetite regulatory system. OBJECTIVE: The aim of this study was to assess the effects of 12 wk of mandatory exercise on appetite control. DESIGN: Fifty-eight overweight and obese men and women [mean (+/-SD) body mass index (in kg/m(2)) = 31.8 +/- 4.5, age = 39.6 +/- 9.8 y, and maximal oxygen intake = 29.1 +/- 5.7 mL . kg(-1) . min(-1)] completed 12 wk of supervised exercise in the laboratory. The exercise sessions were designed to expend 2500 kcal/wk. Subjective appetite sensations and the satiating efficiency of a fixed breakfast were compared at baseline (week 0) and at week 12. An Electronic Appetite Rating System was used to measure subjective appetite sensations immediately before and after the fixed breakfast in the immediate postprandial period and across the whole day. The satiety quotient of the breakfast was determined by calculating the change in appetite scores relative to the breakfast's energy content. RESULTS: Despite large variability, there was a significant reduction in mean body weight (3.2 +/- 3.6 kg), fat mass (3.2 +/- 2.2 kg), and waist circumference (5.0 +/- 3.2 cm) after 12 wk. The analysis showed that a reduction in body weight and body composition was accompanied by an increase in fasting hunger and in average hunger across the day (P < 0.0001). Paradoxically, the immediate and delayed satiety quotient of the breakfast also increased significantly (P < 0.05). CONCLUSIONS: These data show that the effect of exercise on appetite regulation involves at least 2 processes: an increase in the overall (orexigenic) drive to eat and a concomitant increase in the satiating efficiency of a fixed meal.
Authors:
Neil A King; Phillipa P Caudwell; Mark Hopkins; James R Stubbs; Erik Naslund; John E Blundell
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-12
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  90     ISSN:  1938-3207     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-21     Completed Date:  2009-10-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  921-7     Citation Subset:  AIM; IM    
Affiliation:
Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia. n.king@qut.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue
Adult
Appetite / physiology
Appetite Regulation / physiology*
Body Weight
Energy Intake
Exercise*
Female
Humans
Hunger / physiology*
Male
Middle Aged
Obesity / physiopathology,  therapy
Overweight / physiopathology*,  therapy
Satiation / physiology*
Waist Circumference / physiology
Weight Loss / physiology*
Grant Support
ID/Acronym/Agency:
BBS/B/05079//Biotechnology and Biological Sciences Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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