| Dual-probe 24-hour ambulatory pH monitoring for diagnosis of laryngopharyngeal reflux. | |
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MedLine Citation:
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PMID: 15638969 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Patients with gastroesophageal reflux disease may suffer from a variety of symptoms from the upper aerodigestive tract. The objective of this study was to determine the impact of dual-probe 24-hr pH monitoring in the diagnosis of reflux-related otolaryngological disorders. METHODS: Twenty-two patients with symptoms such as chronic cough, globus pharyngeus, heartburn, dysphonia and burning sensation of the tongue underwent a complete ear, nose and throat examination, 24-hr dual-probe pH monitoring, and oesophago-gastro-duodenoscopy. RESULTS: pH monitoring revealed gastroesophageal (distal) reflux in all patients and pharyngeal (proximal) reflux in 21 patients. Treatment consisted of a proton pump inhibitor (esomeprazole). Within 4 weeks 68 per cent of patients had no laryngopharyngeal symptoms; within 8 weeks 95 per cent of patients were symptom-free. CONCLUSIONS: Patients with atypical reflux symptoms such as hoarseness, globus sensation or throat-clearing responded well to anti-reflux treatment. |
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Authors:
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W J Issing; P D Karkos; K Perreas; C Folwaczny; O Reichel |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: The Journal of laryngology and otology Volume: 118 ISSN: 0022-2151 ISO Abbreviation: J Laryngol Otol Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2005-01-10 Completed Date: 2005-03-24 Revised Date: 2013-01-07 |
Medline Journal Info:
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Nlm Unique ID: 8706896 Medline TA: J Laryngol Otol Country: England |
Other Details:
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Languages: eng Pagination: 845-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Otolaryngology, The Freeman Hospital, Newcastle Upon Tyne NE7 7DN, UK. wolfgang.issing@nuth.northy.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anti-Ulcer Agents / therapeutic use Cough / etiology Endoscopy, Gastrointestinal Esomeprazole Sodium / therapeutic use Female Gastroesophageal Reflux / complications, diagnosis*, drug therapy Hoarseness / etiology Humans Hydrogen-Ion Concentration Laryngeal Diseases / diagnosis*, etiology Male Middle Aged Monitoring, Ambulatory / methods* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Ulcer Agents; L2C9GWQ43H/Esomeprazole Sodium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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