| Dual-phase versus single-phase helical CT to detect and assess resectability of pancreatic carcinoma. | |
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MedLine Citation:
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PMID: 12034622 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to compare dual-phase and single-phase helical CT for the detection and assessment of resectability of pancreatic adenocarcinoma. SUBJECTS AND METHODS: We studied 60 patients (31 men, 29 women; age range, 31-84 years; mean age, 62 years) with suspected pancreatic malignancy. Patients were randomly assigned to one of two groups. For group A (n = 30), unenhanced scans through the liver and pancreas were followed by two separate acquisitions (dual-phase) at 20-25 and at 60-80 sec after IV contrast administration. For group B (n = 30), unenhanced scans were followed by one set of scans (single-phase) acquired caudocranially (from the inferior hepatic margin to the diaphragm) starting 50 sec after IV contrast administration. Two observers independently scored images for the presence of tumor and for assessment of tumor resectability. RESULTS: Comparison of dual-phase versus single-phase helical CT for tumor detection showed a diagnostic accuracy for observer 1 of 87% and 90%, respectively, and for observer 2, of 90% and 87%, respectively. For both helical CT techniques, the overall agreement between the two observers was 83% (kappa = 0.73 +/- 0.03) for single-phase helical CT and 90% (kappa = 0.89 +/- 0.03) for dual-phase helical CT. The assessment of resectability was affected by the low number of resectable tumors (n = 8). CONCLUSION: Single-phase helical CT is effective for the diagnosis and assessment of resectability of patients with suspected pancreatic carcinoma. Advantages are the lower radiation dose and fewer images to film and store. |
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Authors:
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Massimo Imbriaco; Alec J Megibow; Luigi Camera; Leonardo Pace; Pier Paolo Mainenti; Maurizio Romano; Guerino Selva; Marco Salvatore |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 178 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-05-29 Completed Date: 2002-07-02 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 1473-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University "Federico II," Via Pansini 5, 80131 Napoli, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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surgery* Adult Aged Aged, 80 and over Female Humans Male Middle Aged Pancreatic Neoplasms / surgery* Prospective Studies Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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