Document Detail

Dual phase MIBI scintigraphy in diagnosis of parathyroid adenoma followed by ultrasound guided percutaneous alcoholic ablation.
MedLine Citation:
PMID:  19610543     Owner:  NLM     Status:  MEDLINE    
Primary Hyperparathyroidism (HPT) is an inappropriate hyper secretion of parathyroid hormone (PTH). Primary HPT is caused by parathyroid adenoma in 80-85% of patients. Clinical manifestations are kidney stones, abdominal groans, painful bones, psychic moans, and fatigue overtones. Ultrasonography is widely used in suspected cases for localization of parathyroid adenoma. There is considerable intra-observer variation and it is difficult for ultrasound alone to differentiate parathyroid lesion form that of thyroid. Dual phase Tc-99m MIBI scinitigraphy for detection of parathyroid adenomas has sensitivity and specificity values ranging from 82% to 100% and from 89% to 100%, respectively. Percutaneous ethanol injection for parathyroid glands can be applied effectively in selected cases when surgery is unadvisable either for technical reasons (e.g., recurrence ofhyperplastic glands in the neck after subtotal surgery or intrathyroideal parathyroid tumors or the poor clinical state of the patient.
Shakil Ahmad; Amjad Aziz Khan Asif Jielani; Kamran Khan; Tatheer Fatima; Nadeem Zia; Mazhar ud Duha; Abdul Samad; Khalid Memon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of Ayub Medical College, Abbottabad : JAMC     Volume:  20     ISSN:  1025-9589     ISO Abbreviation:  J Ayub Med Coll Abbottabad     Publication Date:    2008 Jul-Sep
Date Detail:
Created Date:  2009-07-20     Completed Date:  2009-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8910750     Medline TA:  J Ayub Med Coll Abbottabad     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  149-51     Citation Subset:  IM    
Department of Nuclear Medicine, Institute of Nuclear Medicine, Oncology and Radiotherapy, Mansehra Road Abbottabad, Pakistan.
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MeSH Terms
Adenoma / radionuclide imaging*,  therapy*,  ultrasonography
Catheter Ablation / methods*
Ethanol / therapeutic use*
Parathyroid Neoplasms / radionuclide imaging*,  therapy*,  ultrasonography
Technetium Tc 99m Sestamibi / diagnostic use
Ultrasonography, Interventional
Reg. No./Substance:
0/Radiopharmaceuticals; 109581-73-9/Technetium Tc 99m Sestamibi; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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