Document Detail

MedLine Citation:
PMID:  10937167     Owner:  NLM     Status:  MEDLINE    
A patient with a right occipital arterio-venous malformation (AVM) and seizures heralded by "lights", and experiencing "ecstasy" underwent a right occipital lobectomy after the AVM was embolized. Thereafter, seizures began with motor arrest and lip smacking, but never again with "light and ecstasy". A right temporal lobectomy and electrocorticogram (E.Co.G) were performed under local anesthesia four years after occipital lobectomy. Abundant spiking activity was recorded from the right hippocampus which showed gliosis and neuronal loss in the pathology studies. Electrical stimulation of the lateral and basal temporal cortices failed to elicit the vision of "lights" or the experience of "ecstasy". The patient has had two seizures in the last two years as a result of a lapse in taking his anti-convulsant medication. He now lives alone, seizure-free. The possible abnormally induced functional network organization and structures involved in the production of the "ecstasy" phenomenon are discussed.
C L Vera; S J Patel; W Naso
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Publication Detail:
Type:  Biography; Case Reports; Historical Article; Journal Article    
Journal Detail:
Title:  Epileptic disorders : international epilepsy journal with videotape     Volume:  2     ISSN:  1294-9361     ISO Abbreviation:  Epileptic Disord     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-08-29     Completed Date:  2000-08-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100891853     Medline TA:  Epileptic Disord     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  21-5     Citation Subset:  IM; Q    
Department Neurological Surgery, Medical University of South Carolina, Charleston 29425, USA.
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MeSH Terms
Anticonvulsants / therapeutic use
Embolism / surgery
Epilepsy / psychology*
Famous Persons
Gliosis / physiopathology
Hippocampus / physiopathology
History, 19th Century
Intracranial Arteriovenous Malformations / complications*,  surgery
Occipital Lobe / surgery
Seizures / psychology
Reg. No./Substance:
Personal Name Subject
Personal Name Subject:
F Dostoewsky

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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