Document Detail

Dual-isotope SPET 201Tl rest/99mTc-MIBI stress: one-day protocol for pre-operative myocardial imaging?
MedLine Citation:
PMID:  8177757     Owner:  NLM     Status:  MEDLINE    
We compared the results of a rest 201TI/stress 99mTc-MIBI protocol, both by means of separate single isotope and simultaneous dual isotope acquisition, with a standard stress/rest 99mTc-MIBI 2-day protocol in 11 patients with low probability of CAD and 14 patients with chronic CAD. In patients with CAD 406 segments (sgs) were analysed. In the standard protocol 119 sgs were classified as pathological of which 50.4% were fixed and 49.6% reversible defects. With the MIBI-stress/TI-rest single 33% of 119 pathological sgs were fixed and 67% reversible defects. With the MIBI-stress/TI-rest dual only 20% were fixed and 80% reversible defects. The reversibility of 59 MIBI-stress/MIBI-rest reversible defects was quantified: MIBI-stress/MIBI-rest 35 +/- 16% MIBI-stress/TI-rest single 50 +/- 26% and MIBI-stress/TI-rest dual 48 +/- 22%. The results of 99mTc-MIBI rest and 201TI rest studies in patients with chronic CAD are not the same. Dual-isotope 1-day 201TI-rest/99mTc-MIBI-stress SPET data, acquired separately, may give fast and complete information on myocardial perfusion at stress and rest, respectively, and on myocardial viability.
A Fikrle; H Rösler; E P Ritter; D Lüscher; H Ledermann; T Berthold
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Nuklearmedizin. Nuclear medicine     Volume:  33     ISSN:  0029-5566     ISO Abbreviation:  Nuklearmedizin     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-06-09     Completed Date:  1994-06-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7609387     Medline TA:  Nuklearmedizin     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  135-40     Citation Subset:  IM    
Dept. of Nuclear Medicine, University of Berne/Inselspital, Switzerland.
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MeSH Terms
Heart / radionuclide imaging*
Preoperative Care*
Rest / physiology
Stress, Physiological / physiopathology
Technetium Tc 99m Sestamibi / diagnostic use*
Thallium Radioisotopes / diagnostic use*
Tomography, Emission-Computed, Single-Photon*
Reg. No./Substance:
0/Thallium Radioisotopes; 109581-73-9/Technetium Tc 99m Sestamibi

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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