Document Detail

Dual-energy vs Conventional Computed Tomography in Determining Stone Composition.
MedLine Citation:
PMID:  24548708     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To compare the accuracy between conventional computed tomography (CT) and dual-energy CT (DECT) in predicting stone composition in a blinded, prospective fashion.
METHODS: A total of 32 renal stones with known composition were scanned in vitro, first using standard CT techniques at 120 kilovolt peak (kV[p]) and then using fast-switched kilovolt DECT at 80 and 140 kilovolt peak (kV[p]). For the DECT scan, a spectral curve was created demonstrating the change of Hounsfield units (HU) across the kiloelectron volt spectrum. The composition of each stone was estimated by comparing each sample curve with curves of known materials. To attempt stone determination using single-energy CT, the HU of each stone was compared with ranges reported in previous studies. The accuracy of each method was compared.
RESULTS: Included were 27 stones large enough to allow analysis. Single-energy measurements accurately identified 14 of 27 stones of all composition (52%), whereas the DECT spectral curves correctly identified 20 (74%). When analyzed by stone type, single-energy vs DECT correctly identified 12 vs 12 of the 12 uric acid stones, 2 vs 3 of the 6 struvite stones, 0 vs 3 of the 5 cystine stones, and 0 vs 2 of the 4 calcium oxalate stones, respectively. When simply attempting to differentiate uric acid vs nonuric acid stones, single-energy CT could accurately differentiate only 6 of 15 stones as nonuric acid (40%) compared with 14 of 15 stones (93%) for DECT.
CONCLUSION: DECT appears to be superior to conventional CT in differentiating stone composition and is particularly accurate in differentiating nonuric acid from uric acid stones.
Eric S Wisenbaugh; Robert G Paden; Alvin C Silva; Mitchell R Humphreys
Related Documents :
21274968 - Cardiovascular mri for the assessment of heart failure: focus on clinical management an...
23637718 - Correction: probabilistic mri brain anatomical atlases based on 1,000 chinese subjects.
24288398 - Paediatric post-septal and pre-septal cellulitis: 10-year experience at a tertiary-leve...
11241748 - Re-creating ancient hominid virtual endocasts by ct-scanning.
24676668 - Influence of iterative image reconstruction on ct-based calcium score measurements.
8462248 - Radiologic manifestations of bronchogenic cancer.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-15
Journal Detail:
Title:  Urology     Volume:  -     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-2-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Long-term Follow-up After Transurethral Treatment of Infravesical Obstruction in Boys.
Next Document:  The Influence of Skull Base Chordoma on Lower Urinary Tract Symptoms.