Document Detail


Dual-energy CT angiography of the lungs: Comparison of test bolus and bolus tracking techniques for the determination of scan delay.
MedLine Citation:
PMID:  20621430     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To prospectively compare test bolus and bolus tracking for the determination of scan delay of pulmonary dual-energy CT angiography in patients with suspected pulmonary embolism.
MATERIALS AND METHODS: 60 consecutive patients referred for CTA for exclusion of PE were randomized either into a test bolus group or into a bolus tracking group. All exams were performed on a 64-channel dual source CT scanner. A standard single-acquisition dual-energy CTA was performed after injection of 100ml Iomeprol 400 followed by a saline chaser of 4ml/s. The scan delay was determined using either test bolus (n=30) or bolus tracking (n=30). Test bolus was performed using an additional 20ml Iomeprol 400 injected with a rate of 4ml/s during acquisition of a series of dynamic low-dose monitoring scans followed by injection of a saline bolus of 20ml using the same flow rate. For DECT angiography of the lungs 100ml Iomeprol 400 was injected with an injection rate of 4ml/s followed by a saline chaser of 20ml using the same flow rate. Attenuation profiles of different vascular segments (pulmonary arteries, pulmonary parenchyma, aorta, all 4 heart chambers) were measured to evaluate the timing techniques. Overall image quality of dual-energy "perfusion" maps and virtual 120kV CTA images was evaluated by two radiologists regarding the present of artifacts.
RESULTS: In all patients an adequate and homogeneous contrast enhancement of more than 400 Hounsfield units (HU) was achieved in the different vascular districts. No statistically significant difference between test bolus and bolus tracking was found regarding vessel attenuation or overall image quality.
CONCLUSION: A homogeneous opacification of the different vascular territories and the pulmonary parenchyma as well as a sufficient image quality can be achieved with either bolus tracking or test bolus techniques.
Authors:
Thomas Henzler; Mathias Meyer; Miriam Reichert; Radko Krissak; John W Nance; Stefan Haneder; Stefan O Schoenberg; Christian Fink
Publication Detail:
Type:  Journal Article     Date:  2010-07-10
Journal Detail:
Title:  European journal of radiology     Volume:  81     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-01-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  132-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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