Document Detail


Dual-demand pacing for refractory atrioventricular re-entry tachycardia.
MedLine Citation:
PMID:  95273     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An automatic dual-demand pacemaker has been used in six patients to treat refractory attacks of paroxysmal re-entry atrioventricular tachycardia that occurred in the Wolff-Parkinson-White syndrome. The pacemaker was designed to pace at a fixed rate of 70 beats per minute when sensed heart rates were either below this rate or above 150 beats per minute; in the latter case, it would compete with the paroxysmal tachycardia and interrupt it after a short period of random scaning. The best location for the permanent pacing electrode and the feasibility of using the pacemaker were tested in each case during a detailed preliminary intracardiac electrophysiological study. The permanent pacing electrode was positioned in the coronary sinus in three patients and was attached to the epicardium of either the left or right ventricle in another three. All patients were given regular oral doses of verapamil or propranolol to enhance the effectiveness of the pacemaker system and, with the latter, to prevent pacemaker activation during sinus tachycardia. Over a follow-up period of between 11 and 47 months, the pacemaker system remained completely effective in three patients, but developed unreliable sensing in another two (one coronary sinus and one left ventricular lead). In the sixth patient the pacemaker was only effective when the rate of the tachycardia remained below 170 beats a minute, as when she was resting supine; when sitting or standing, however, her tachycardia rate considerably exceeded this value and the pacemaker was ineffective. Explantation of the pacemaker and either successful cryosurgical ablation of the accesory AV pathway or treatment with amiodarone was undertaken in the three patients in whom the pacemaker had failed.
Authors:
P V Curry; E Rowland; D M Krikler
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  2     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1979 Mar 
Date Detail:
Created Date:  1980-12-18     Completed Date:  1980-12-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  137-51     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Amiodarone / therapeutic use
Electrocardiography
Female
Follow-Up Studies
Heart Conduction System / drug effects
Heart Ventricles / physiopathology
Humans
Male
Middle Aged
Pacemaker, Artificial*
Propranolol / therapeutic use
Sick Sinus Syndrome / complications
Sinus of Valsalva / physiopathology
Tachycardia, Paroxysmal / therapy*
Time Factors
Verapamil / therapeutic use
Wolff-Parkinson-White Syndrome / complications*
Chemical
Reg. No./Substance:
1951-25-3/Amiodarone; 52-53-9/Verapamil; 525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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