Document Detail


Dry- and wet-ashing techniques compared in analyses for zinc, copper, manganese, and iron in hair.
MedLine Citation:
PMID:  3698264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Preparation of hair specimens for trace-metal analyses is routinely done by wet- or dry-ashing. Wet-ashing is more time consuming than dry-ashing and can be dangerous. We wished to determine if dry-ashing was a suitable alternative to wet-ashing with HClO4:HNO3 or HNO3 alone in preparing hair for measurement of zinc, copper, iron, and manganese by atomic absorption spectroscopy. Concentrations of Zn, Cu, and Mn were not differently affected in hair that was dry- or wet-ashed. Analytical recovery of these elements added to hair samples ranged from 102 to 108%; day-to-day CVs were less than 5%. Fe was lost during dry-ashing of hair, and wet-ashing with HNO3 produced results for Fe comparable with those obtained with HClO4:HNO3. Therefore we recommend dry-ashing of hair to be analyzed for Zn, Cu, and Mn, but wet-ashing with HNO3 for assays of Fe.
Authors:
J K Friel; C D Ngyuen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical chemistry     Volume:  32     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-06-16     Completed Date:  1986-06-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  739-42     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Copper / analysis*
Female
Hair / analysis*
Humans
Iron / analysis*
Male
Manganese / analysis*
Methods
Neural Tube Defects / metabolism
Spectrophotometry, Atomic
Zinc / analysis*
Chemical
Reg. No./Substance:
7439-89-6/Iron; 7439-96-5/Manganese; 7440-50-8/Copper; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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