| Drugs in pregnancy. Anticoagulants. | |
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MedLine Citation:
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PMID: 11800528 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pregnancy is a period of heightened coagulability and enhanced risk for thrombotic complications. Thromboembolism is the leading cause of maternal mortality. Anticoagulants are very useful during pregnancy for the acute treatment of venous thromboembolism and for the prevention of recurrent venous thromboembolism. They may also be beneficial in patients with thrombophilias, particularly among women who have experienced adverse pregnancy outcomes such as recurrent pregnancy loss. Anticoagulation is essential but problematic in the management of pregnant women with mechanical heart valve prostheses. When utilizing these medications among pregnant women the potential benefits must be balanced against the possibility of maternal haemorrhagic complications, adverse effects on the pregnancy or toxic effects on the fetus. This chapter summarizes current knowledge about the anticoagulant agents, their potential toxicities and their therapeutic role in pregnant women with various indications for anticoagulant therapy. |
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Authors:
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P S Gibson; K Rosene-Montella |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Best practice & research. Clinical obstetrics & gynaecology Volume: 15 ISSN: 1521-6934 ISO Abbreviation: Best Pract Res Clin Obstet Gynaecol Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2002-01-21 Completed Date: 2002-01-31 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 101121582 Medline TA: Best Pract Res Clin Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 847-61 Citation Subset: IM |
Copyright Information:
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Copyright 2001 Harcourt Publishers Ltd. |
Affiliation:
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Division of Obstetric and Consultative Medicine, Department of Medicine, Women and Infants' Hospital of Rhode Island and Brown University School of Medicine, Providence 02095, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Habitual
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prevention & control Anticoagulants / therapeutic use* Female Heart Valve Prosthesis / adverse effects Humans Pregnancy Pregnancy Complications, Hematologic / prevention & control* Thromboembolism / prevention & control* Thrombophilia / drug therapy Venous Thrombosis / prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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