Document Detail

Drugs, exercise, and the melanocortin-4 receptor- different means, same ends: treating obesity.
MedLine Citation:
PMID:  21222259     Owner:  NLM     Status:  In-Data-Review    
As the percentage of obese humans expands, new options for weight loss are being explored. Body weight homeostasis is the result of a balance between energy intake (food) and expenditure (activity). A shift in homeostasis into a negative balance results in weight loss. Two potential options available for the management of body weight, as related to the melanocortin system, are exercise (increase energy expenditure) and drugs targeting the melanocortin-4 receptors for satiety.
Jay W Schaub; Erin B Bruce; Carrie Haskell-Luevano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  681     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  2010  
Date Detail:
Created Date:  2011-01-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  49-60     Citation Subset:  IM    
Department of Pharmacodynamics, University of Florida, PO Box 100487, Gainesville, Florida, 32610-0487, USA.
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