| Drug utilization review on a surgical intensive care unit. | |
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MedLine Citation:
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PMID: 7820326 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Drug use reviews (DUR) provide information about drug prescription patterns. At the surgical intensive care unit (SICU) of the University Hospital Frankfurt/Main we recorded the indication related administration of blood products and pharmaceuticals (which were responsible for 60% of the total costs at the SICU in the year before) over a 4-month investigation period. Data were recorded and analyzed using a notebook-PC. 207 Patients were included, and recorded total expenditures came to $551,592. The 10 leading substances, represented by antibiotics and blood-products, caused more than 70% of total costs. The usage of these high-cost substances and the most expensive complications are identified and discussed. We concluded that DURs are useful for obtaining information about drug usage patterns and for identifying high cost drugs, which are of economic interest. Furthermore, the indications for the application of these substances can be identified. Our results suggest, that blood and blood-products should always be included in DURs. In our opinion, especially the usage of blood-products represents a field where considerable cost savings may be expected. As certain complications during the postoperative course (e.g. sepsis) may increase costs, they should be considered in the reimbursement negotiations between hospitals and health insurance. |
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Authors:
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J P Marschner; P Thürmann; S Harder; N Rietbrock |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of clinical pharmacology and therapeutics Volume: 32 ISSN: 0946-1965 ISO Abbreviation: Int J Clin Pharmacol Ther Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1995-02-10 Completed Date: 1995-02-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9423309 Medline TA: Int J Clin Pharmacol Ther Country: GERMANY |
Other Details:
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Languages: eng Pagination: 447-51 Citation Subset: IM |
Affiliation:
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Department of Clinical Pharmacology, University Hospital Frankfurt/Main. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anti-Bacterial Agents / economics* Biological Products / economics* Blood Coagulation Factors / economics Cost-Benefit Analysis Data Collection Drug Costs Drug Prescriptions / economics, standards* Drug Utilization Review* Female Germany Humans Immunoglobulin M / economics Intensive Care Units / economics*, standards Male Middle Aged Serum Albumin / economics Surgery Department, Hospital / economics, standards |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Biological Products; 0/Blood Coagulation Factors; 0/Immunoglobulin M; 0/Serum Albumin; 37224-63-8/prothrombin complex concentrates |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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