| Drug users and HIV-combination therapy (HAART): factors which impede or facilitate adherence. | |
| | |
MedLine Citation:
|
PMID: 12511058 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The current highly active antiretroviral therapy (HAART), i.e., triple combination treatment including a protease inhibitor, allows for long-term suppression of HIV-replication. The intake guidelines, however, are very strict and, like many other HIV positive patients, drug users have problems in achieving good therapy compliance. As a result, the effectiveness of the medication therapy is seriously jeopardized. This qualitative study, involving in-depth interviews with 27 "hard drug" users in Amsterdam, seeks to provide better insights into the extent of adherence to HAART. In addition, factors that impede or facilitate adherence have been listed in order to develop and improve strategies. The study shows that almost half of the "hard drug" users interviewed do not adhere to the therapy. A large number of determinants for adherence were identified at the level of medication, the individual, and the environment. Many of these determinants can be influenced, which means that they can provide clues for the effective implementation of measures that may enhance effectiveness of treatment. |
| | |
Authors:
|
Ewald Witteveen; Erik J C van Ameijden |
Related Documents
:
|
15482138 - Tenofovir disoproxil fumarate (viread) for the treatment of hiv infection. 18771638 - New therapeutic agents in the management of hiv: an overview of darunavir for clinicians. 15228148 - Therapeutic drug monitoring for patients with hiv infection: children's national medica... 17472538 - Access denied? the status of co-receptor inhibition to counter hiv entry. 6145028 - Captopril: a new treatment for rheumatoid arthritis? 16534208 - Vascular dementia: potential of antiplatelet agents in prevention. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Substance use & misuse Volume: 37 ISSN: 1082-6084 ISO Abbreviation: Subst Use Misuse Publication Date: 2002 |
Date Detail:
|
Created Date: 2003-01-03 Completed Date: 2003-05-01 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9602153 Medline TA: Subst Use Misuse Country: United States |
Other Details:
|
Languages: eng Pagination: 1905-25 Citation Subset: IM |
Affiliation:
|
Cluster Infectious Diseases, Municipal Health Service, Nieuwe Achtergracht 100, 1018 WT Amsterdam, The Netherlands. ewitteveen@gggd.amsterdam.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Antiretroviral Therapy, Highly Active / psychology* Combined Modality Therapy Female HIV Infections / drug therapy* Health Knowledge, Attitudes, Practice Humans Interview, Psychological Male Methadone / therapeutic use* Middle Aged Patient Compliance / psychology* Social Support Substance-Related Disorders / psychology, therapy* |
| Chemical | |
Reg. No./Substance:
|
76-99-3/Methadone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Alcoholic liver disease (ALD): a new domain for prevention efforts.
Next Document: Treating cocaine-using methadone patients: predictors of outcomes in a psychosocial clinical trial.