Document Detail


Drug targeting in magnetic resonance imaging.
MedLine Citation:
PMID:  1567758     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This review summarizes the attempts of drug targeting in the field of magnetic resonance imaging. Although the field is young and most work is performed in nonspecific lanthanide chelates, it is obvious that target selectivity and receptor and/or antigen specificity is the most important issue if functional magnetic resonance imaging is to establish itself in the next decade. Recent advances in biochemical engineering and magnetic resonance research have made targeting of diagnostic drugs a credible alternative to conventional drug use in magnetic resonance imaging.
Authors:
R Weissleder; A Bogdanov; M Papisov
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Magnetic resonance quarterly     Volume:  8     ISSN:  0899-9422     ISO Abbreviation:  Magn Reson Q     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-05-27     Completed Date:  1992-05-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8910769     Medline TA:  Magn Reson Q     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  55-63     Citation Subset:  IM    
Affiliation:
MGH-NMR Center, Department of Radiology, Massachusetts General Hospital, Boston 02114.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibodies, Monoclonal / diagnostic use
Carrier Proteins / chemistry
Contrast Media*
Drug Carriers*
Humans
Iron Chelating Agents / diagnostic use
Liposomes
Magnetic Resonance Imaging / methods*
Rats
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Carrier Proteins; 0/Contrast Media; 0/Drug Carriers; 0/Iron Chelating Agents; 0/Liposomes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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