Document Detail

Drug-resistant temporal lobe epilepsy is associated with postural control abnormalities.
MedLine Citation:
PMID:  21474386     Owner:  NLM     Status:  Publisher    
Epilepsy is responsible for falls that are not systematically associated with seizures and that therefore suggest postural impairment. There are very few studies of postural control in patients with epilepsy and none of them focus on temporal lobe epilepsy (TLE), although part of the vestibular cortex is located in the temporal cortex. The aim of this study was to evaluate the characteristics of postural control in a homogeneous population of patients with complex partial TLE. Twenty-six patients with epilepsy and 26 age-matched healthy controls underwent a sensory organization test combining six conditions, with and without sensory conflicting situations. Patients with epilepsy displayed poorer postural control, especially in situations where vestibular information is necessary to control balance. In addition to potential antiepileptic drug side effects, vestibular dysfunction could be related to the temporal pathology. Our study allows for a better understanding of the mechanism underlying falls in this population of patients.
S Colnat-Coulbois; G C Gauchard; L Maillard; J P Vignal; H Vespignani; J Auque; Ph P Perrin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-5
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  -     ISSN:  1525-5069     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Balance Control and Motor Performance, UFR STAPS, Henri Poincaré University Nancy I, Villers-lès-Nancy, France; Thematic Group "Neurodegenerative Diseases, Neuroplasticity, Cognition," Faculty of Medicine, INSERM U 954, Vandoeuvre-lès-Nancy, France; Department of Neurosurgery, University Hospital of Nancy, Nancy, France.
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