| Drug interactions in hypertensive patients. Pharmacokinetic, pharmacodynamic and genetic considerations. | |
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MedLine Citation:
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PMID: 2182265 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Antihypertensive treatment has proven benefits, and the number of patients being treated with these drugs is significant. Hypertensive patients may have other medical illnesses for which they receive medications, and interactions between antihypertensive agents and other drugs is likely. Some of these interactions may lead to undesirable effects or even loss of blood pressure control. However, drug interactions can also be beneficial when 2 antihypertensive drugs with different pharmacological actions are prescribed in combination and with a clear therapeutic objective in mind. Clinicians should be aware of the mechanisms and the consequences of the different types of interaction in hypertensive patients, so that a desired pharmacological response can be achieved with the fewest side effects in the patients. |
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Authors:
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Y W Lam; A M Shepherd |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical pharmacokinetics Volume: 18 ISSN: 0312-5963 ISO Abbreviation: Clin Pharmacokinet Publication Date: 1990 Apr |
Date Detail:
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Created Date: 1990-05-17 Completed Date: 1990-05-17 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7606849 Medline TA: Clin Pharmacokinet Country: NEW ZEALAND |
Other Details:
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Languages: eng Pagination: 295-317 Citation Subset: IM |
Affiliation:
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Department of Pharmacology, University of Texas Health Science Center, San Antonio. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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pharmacokinetics*,
pharmacology Drug Interactions Drug Therapy, Combination Female Humans Hypertension / drug therapy, genetics, metabolism* Male Pharmacogenetics* |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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